Measurements included demographic information; pain scores on a verbal numeric rating scale at baseline and at 30 and 60 minutes; vital signs at baseline and at 30 and 60 minutes; and adverse effects.
Results: Seventy-three subjects were randomized to receive oxycodone or hydrocodone. There was no difference between the two groups in age, weight, gender, ethnicity, diagnoses, baseline pain scores, or vital signs. Patients in both groups had pain relief from baseline to 30 minutes oxycodone mean change 3.
Many people believe oxycodone to be a better pain reliever than hydrocodone. A study set out to compare the effectiveness of an oxycodone and acetaminophen drug combination with that of a hydrocodone and acetaminophen drug combination.
The study found no significant differences between the two drug combinations with regard to treating acute musculoskeletal pain. Both oxycodone and hydrocodone are effective in reducing pain sensations. However, they will not address the underlying cause of the pain.
Due to the risks of dependence and addiction, many experts recommend exploring other pain options before taking opioids. Some possible side effects of these medications include :. Research has shown that oxycodone-acetaminophen combinations are more likely than hydrocodone-acetaminophen combinations to induce nausea and dizziness. People who take any opioid medication for a significant amount of time may experience drug tolerance. This effect means that a person needs to take increasing amounts of a medication for it to achieve the same effect.
Tolerance increases the risk of substance abuse. People who stop taking an opioid drug may experience withdrawal, especially if they have been taking high doses of the drug or have been taking it for an extended period. Withdrawal occurs because the body is learning to adjust to the absence of opioids in its system. Some potential symptoms of opioid withdrawal include:.
Hydrocodone and oxycodone can interact with many different drugs, including some medications belonging to the following groups:.
Opioid medications also interact with alcohol and some recreational drugs, as well as certain supplements. To avoid the risk of drug interactions, a person should provide their doctor with detailed information about all of the prescription medications and over-the-counter OTC supplements that they are taking. They should also refrain from drinking alcohol or using recreational drugs while taking either oxycodone or hydrocodone.
Both oxycodone and hydrocodone can lead to dependency and addiction , especially if a person takes either drug at a high dose or for an extended period. Over time, people may develop a tolerance to oxycodone or hydrocodone.
In an effort to sustain their pain relief, they may begin taking the drug more frequently or taking a dose that is higher than their doctor prescribed.
Opioid abuse is a major public health problem. Since hydrocodone is more potent and has a higher potential for abuse, it is thought to be more addictive than codeine.
However, both drugs are dangerous when abused and can lead to physical dependence, addiction, and overdose. Using prescription opioids in combination with alcohol or other sedatives may increase the risk of addiction, respiratory depression, and overdose. Regardless of the potency, opioids are highly addictive when abused. Pick up the phone and call now to speak to a dedicated treatment provider to learn about your drug rehab options.
All of the information on this page has been reviewed and verified by a certified addiction professional. She currently practices in the public domain in South Africa.
She has an interest in medical writing and has a keen interest in evidence-based medicine. Codeine vs. Table of Contents. Share Tweet Pin. Medically Reviewed: September 25, The combination of alcohol and painkillers can cause extreme dizziness or drowsiness.
The combination can also damage your liver. A study published in the American Journal of Obstetrics and Gynecology found that there was an association between opioid treatment and certain birth defects. Also, some of the side effects of the medication could cause problems for you while you are pregnant. These side effects include behavior changes, difficulty breathing, constipation, and lightheadedness. They can pass through breast milk and harm your baby.
Even at low levels and when taken exactly as prescribed, these medications can be habit-forming. Misuse of these narcotics can lead to addiction, poisoning, overdose, or even death. Both hydrocodone and oxycodone are effective at easing acute and chronic pain. They both cause very similar side effects. The differences between the two drugs are minimal, so the best way to pick which drug is right for you is by having a conversation with your doctor.
Based on your personal medical history, your doctor can weigh the pros and cons of the two medications. Some researchers and medical professionals find that hydrocodone is less powerful compared to oxycodone. In that case, your doctor may prefer to start you on a smaller dose to see how your body handles the medication.
The list of opioids is long. Learn their forms, factors used in choosing them, and tips for taking them safely. Vicodin and Percocet are two powerful painkillers prescribed for short-term pain relief. See how the two compare and learn about their differences. OxyContin is the extended-release form of oxycodone.
Codeine and hydrocodone both treat pain, but one may be better suited for you depending on the severity of your pain. To avoid the side effects and possible toxicity of medications, you might turn to natural painkillers instead. Check out these five surprising options. Opioid addiction can cause serious health issues and can lead to death. Read more on addiction and how to quit. Learn about the most addictive prescription drugs, including Adderall and Xanax.
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